BDBM50148050 (1E)-1-(4-phenoxyphenyl)ethan-1-one thiosemicarbazone::CHEMBL109893

SMILES CC(=NNC(N)=S)c1ccc(Oc2ccccc2)cc1

InChI Key InChIKey=WHIVBHRWDXJLBI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50148050   

TargetCruzipain(Trypanosoma cruzi)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50148050((1E)-1-(4-phenoxyphenyl)ethan-1-one thiosemicarbaz...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of cruzain from Trypanosoma cruziMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50148050((1E)-1-(4-phenoxyphenyl)ethan-1-one thiosemicarbaz...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of rhodesain from Trypanosoma brucei rhodesienseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50148050((1E)-1-(4-phenoxyphenyl)ethan-1-one thiosemicarbaz...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant Trypanosoma cruzi Cruzipain using Z-Phe-Arg-AMC as substrate preincubated for 5 mins followed by substrate addition by spec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed