BDBM50147857 CHEMBL103208::[(3R,4S)-4-(4-Chloro-phenyl)-1-methyl-piperidin-3-yl]-acetic acid 3-phenyl-propyl ester

SMILES CN1CC[C@@H]([C@@H](CC(=O)OCCCc2ccccc2)C1)c1ccc(Cl)cc1

InChI Key InChIKey=HXKOFQYJBUCYAA-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50147857   

TargetSodium-dependent dopamine transporter(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50147857([(3R,4S)-4-(4-Chloro-phenyl)-1-methyl-piperidin-3-...)
Affinity DataKi:  36nMAssay Description:Ability to inhibit high affinity uptake of [3H]DA at Dopamine transporter (DAT) using rat brain striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50147857([(3R,4S)-4-(4-Chloro-phenyl)-1-methyl-piperidin-3-...)
Affinity DataKi:  48nMAssay Description:Ability to inhibit high affinity uptake of [3H]NE at Norepinephrine transporter (NET) using rat brain parietal/occipital cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50147857([(3R,4S)-4-(4-Chloro-phenyl)-1-methyl-piperidin-3-...)
Affinity DataKi:  82nMAssay Description:Ability to inhibit high affinity uptake of [3H]-5-HT at Serotonin transporter (SERT) using rat midbrainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed