BDBM50147851 (3R,4S)-4-(4-Chloro-phenyl)-1-methyl-3-propyl-piperidine::CHEMBL103829

SMILES CCC[C@H]1CN(C)CC[C@@H]1c1ccc(Cl)cc1

InChI Key InChIKey=MWGRXFWGMDSMNI-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50147851   

TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50147851((3R,4S)-4-(4-Chloro-phenyl)-1-methyl-3-propyl-pipe...)
Affinity DataIC50: 17nMAssay Description:Ability to displace [3H]WIN-35428 binding to dopamine transporter from rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50147851((3R,4S)-4-(4-Chloro-phenyl)-1-methyl-3-propyl-pipe...)
Affinity DataIC50: 23nMAssay Description:Inhibition of high-affinity uptake of [3H]dopamine at dopamine transporter into rat striatal nerve endings (synaptosomes)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50147851((3R,4S)-4-(4-Chloro-phenyl)-1-methyl-3-propyl-pipe...)
Affinity DataKi:  6.5nMAssay Description:Ability to inhibit high affinity uptake of [3H]NE at Norepinephrine transporter (NET) using rat brain parietal/occipital cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50147851((3R,4S)-4-(4-Chloro-phenyl)-1-methyl-3-propyl-pipe...)
Affinity DataKi:  20nMAssay Description:Ability to inhibit high affinity uptake of [3H]DA at Dopamine transporter (DAT) using rat brain striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50147851((3R,4S)-4-(4-Chloro-phenyl)-1-methyl-3-propyl-pipe...)
Affinity DataKi:  228nMAssay Description:Ability to inhibit high affinity uptake of [3H]-5-HT at Serotonin transporter (SERT) using rat midbrainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed