BDBM50147846 (3R,4S)-3-(5-Benzo[1,3]dioxol-5-yl-[1,2,4]oxadiazol-3-ylmethyl)-4-(4-chloro-phenyl)-1-methyl-piperidine::CHEMBL316749

SMILES CN1CC[C@@H]([C@@H](Cc2noc(n2)-c2ccc3OCOc3c2)C1)c1ccc(Cl)cc1

InChI Key InChIKey=XTLRIYLTSUYNOM-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50147846   

TargetSodium-dependent serotonin transporter(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50147846((3R,4S)-3-(5-Benzo[1,3]dioxol-5-yl-[1,2,4]oxadiazo...)
Affinity DataKi:  32nMAssay Description:Ability to inhibit high affinity uptake of [3H]-5-HT at Serotonin transporter (SERT) using rat midbrainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50147846((3R,4S)-3-(5-Benzo[1,3]dioxol-5-yl-[1,2,4]oxadiazo...)
Affinity DataKi:  44nMAssay Description:Ability to inhibit high affinity uptake of [3H]DA at Dopamine transporter (DAT) using rat brain striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50147846((3R,4S)-3-(5-Benzo[1,3]dioxol-5-yl-[1,2,4]oxadiazo...)
Affinity DataKi:  52nMAssay Description:Ability to inhibit high affinity uptake of [3H]NE at Norepinephrine transporter (NET) using rat brain parietal/occipital cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed