BDBM50147744 1-{1-[1-(4-Cyclohexyl-phenyl)-ethyl]-piperidin-4-yl}-1,3-dihydro-indol-2-one::CHEMBL97979

SMILES CC(N1CCC(CC1)N1C(=O)Cc2ccccc12)c1ccc(cc1)C1CCCCC1

InChI Key InChIKey=KVNPCTLYRRUZDP-UHFFFAOYSA-N

Data  5 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50147744   

TargetNociceptin receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50147744(1-{1-[1-(4-Cyclohexyl-phenyl)-ethyl]-piperidin-4-y...)
Affinity DataEC50: >1.00E+4nMAssay Description:Concentration required for stimulation of [35S]GTP-gamma-S, binding to human Nociceptin receptor in cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50147744(1-{1-[1-(4-Cyclohexyl-phenyl)-ethyl]-piperidin-4-y...)
Affinity DataKi:  210nMAssay Description:Binding affinity against human Opioid receptor mu 1 on CHO cell membranes was determined by [3H]DAMGO displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50147744(1-{1-[1-(4-Cyclohexyl-phenyl)-ethyl]-piperidin-4-y...)
Affinity DataKi:  253nMAssay Description:Binding affinity against human Nociceptin receptor on CHO cell membranes by [3H]N/OFQ displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50147744(1-{1-[1-(4-Cyclohexyl-phenyl)-ethyl]-piperidin-4-y...)
Affinity DataKi:  3.87E+3nMAssay Description:Binding affinity against human Opioid receptor kappa 1 on CHO cell membranes by [3H]U-69593 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50147744(1-{1-[1-(4-Cyclohexyl-phenyl)-ethyl]-piperidin-4-y...)
Affinity DataKi:  1.00E+4nMAssay Description:Displacement of [3H]epibatidine from rat alpha3beta4 nAChR expressed in HEK292 cells after 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
LigandPNGBDBM50147744(1-{1-[1-(4-Cyclohexyl-phenyl)-ethyl]-piperidin-4-y...)
Affinity DataKi:  1.00E+4nMAssay Description:Displacement of [3H]epibatidine from rat alpha4beta2 nAChR expressed in HEK292 cells after 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed