BDBM50147706 CHEMBL114584::[3-Amino-3-hydroxymethyl-5-(4-octyl-phenyl)-pentyl]-phosphonic acid

SMILES CCCCCCCCc1ccc(CCC(N)(CO)CCP(O)(O)=O)cc1

InChI Key InChIKey=XDSPSYJWGHPIAZ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50147706   

TargetSphingosine 1-phosphate receptor 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50147706([3-Amino-3-hydroxymethyl-5-(4-octyl-phenyl)-pentyl...)
Affinity DataIC50: 510nMAssay Description:Inhibition of [33P]-S1P binding to human Sphingosine 1-phosphate receptor 3 expressed on CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50147706([3-Amino-3-hydroxymethyl-5-(4-octyl-phenyl)-pentyl...)
Affinity DataIC50: 8.70nMAssay Description:Inhibition of [33P]-S1P binding to human Sphingosine 1-phosphate receptor 1 expressed on CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50147706([3-Amino-3-hydroxymethyl-5-(4-octyl-phenyl)-pentyl...)
Affinity DataIC50: 230nMAssay Description:Inhibition of [33P]-S1P binding to human Sphingosine 1-phosphate receptor 5 expressed on CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50147706([3-Amino-3-hydroxymethyl-5-(4-octyl-phenyl)-pentyl...)
Affinity DataIC50: 210nMAssay Description:Inhibition of [33P]-S1P binding to human Sphingosine 1-phosphate receptor 4 expressed on CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50147706([3-Amino-3-hydroxymethyl-5-(4-octyl-phenyl)-pentyl...)
Affinity DataIC50: 7nMAssay Description:Displacement of [33P]-S1P from S1P3 receptor (unknown origin) expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2019
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50147706([3-Amino-3-hydroxymethyl-5-(4-octyl-phenyl)-pentyl...)
Affinity DataIC50: 6nMAssay Description:Displacement of [33P]-S1P from S1P1 receptor (unknown origin) expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2019
Entry Details Article
PubMed