BDBM50147684 CHEMBL3765105

SMILES COc1ccc(cc1)-c1cccc2c1oc(nc2=O)N1CCOCC1

InChI Key InChIKey=XZHOMAAPWRRUNV-UHFFFAOYSA-N

Data  3 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50147684   

TargetDNA-dependent protein kinase catalytic subunit(Human)
La Trobe University

Curated by ChEMBL

LigandBDBM50147684(CHEMBL3765105)Copy SMILESCopy InChI

Affinity DataIC50: 9.94E+3nMAssay Description:Inhibition of human DNA-PK using EPPLSQEAFADLWKK as substrate by HTRF assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
6/19/2017
Entry Details Article
Copy Entry DOIPubMed
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
La Trobe University

Curated by ChEMBL

LigandBDBM50147684(CHEMBL3765105)Copy SMILESCopy InChI

Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of PI3Kdelta (unknown origin) incubated for 60 mins by kinase-glo luminescence assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
6/19/2017
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
La Trobe University

Curated by ChEMBL

LigandBDBM50147684(CHEMBL3765105)Copy SMILESCopy InChI

Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin) incubated for 60 mins by kinase-glo luminescence assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
6/19/2017
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL