BDBM50147676 CHEMBL3763878

SMILES O=c1nc(oc2c(cccc12)-c1cc2ccccc2s1)N1CCOCC1

InChI Key InChIKey=GRUKVISAMVIBMY-UHFFFAOYSA-N

Data  3 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50147676   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
La Trobe University

Curated by ChEMBL

LigandBDBM50147676(CHEMBL3763878)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PI3Kalpha (unknown origin) incubated for 60 mins by kinase-glo luminescence assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
6/19/2017
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
La Trobe University

Curated by ChEMBL

LigandBDBM50147676(CHEMBL3763878)Copy SMILESCopy InChI

Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of PI3Kdelta (unknown origin) incubated for 60 mins by kinase-glo luminescence assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
6/19/2017
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetDNA-dependent protein kinase catalytic subunit(Human)
La Trobe University

Curated by ChEMBL

LigandBDBM50147676(CHEMBL3763878)Copy SMILESCopy InChI

Affinity DataIC50: 2.12E+3nMAssay Description:Inhibition of human DNA-PK using EPPLSQEAFADLWKK as substrate by HTRF assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
6/19/2017
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL