BDBM50147615 CHEMBL3764876

SMILES OC(=O)CN(c1cccc(c1)-c1cccc(Cl)c1Cl)S(=O)(=O)c1ccc(OC(F)F)cc1

InChI Key InChIKey=VHRMEONQZIUMOQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50147615   

TargetDiacylglycerol lipase-beta(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50147615(CHEMBL3764876)
Affinity DataIC50: 40nMAssay Description:Inhibition of DAGLbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50147615(CHEMBL3764876)
Affinity DataIC50: 14nMAssay Description:Inhibition of full length human C-terminal HA-tagged DAGLalpha expressed in HEK293 cells using DAG as substrate assessed as reduction in intracellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50147615(CHEMBL3764876)
Affinity DataIC50: 14.3nMAssay Description:Inhibition of full length human C-terminal HA-tagged DAGLalpha expressed in HEK293 cells using DAG as substrate assessed as reduction in intracellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed