BDBM50147079 4-Pentyl-N-pyridin-3-yl-benzamide::4-pentyl-N-pyridin-3-yl benzamide::CHEMBL321932

SMILES CCCCCc1ccc(cc1)C(=O)Nc1cccnc1

InChI Key InChIKey=DZLXEBWNAFQZQI-UHFFFAOYSA-N

Data  1 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50147079   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50147079(4-Pentyl-N-pyridin-3-yl-benzamide | 4-pentyl-N-pyr...)
Affinity DataEC50:  900nMAssay Description:Increased [Ca2+] influx in human vanilloid receptor subtype 1 expressing HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50147079(4-Pentyl-N-pyridin-3-yl-benzamide | 4-pentyl-N-pyr...)
Affinity DataEC50:  1.70E+3nMAssay Description:Activity at human TRPV1 in HEK cells assessed by measuring capsaicin-induced calcium level by FLIPR technologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50147079(4-Pentyl-N-pyridin-3-yl-benzamide | 4-pentyl-N-pyr...)
Affinity DataKi:  421nMAssay Description:Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed