BDBM50146940 CHEMBL3765155

SMILES CN1CCN(CCCOc2ccc(cc2)N2C(=S)S\C(=C/c3ccc(Oc4ccc(cc4)[N+]([O-])=O)cc3)C2=O)CC1

InChI Key InChIKey=IPXRZZWLNNGCCT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50146940   

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
The Catholic University of Korea

Curated by ChEMBL
LigandPNGBDBM50146940(CHEMBL3765155)
Affinity DataIC50: 790nMAssay Description:Inhibition of IKKbeta (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2017
Entry Details Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Mouse)
The Catholic University of Korea

Curated by ChEMBL
LigandPNGBDBM50146940(CHEMBL3765155)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of IKKbeta in primary type-2 collagen immunized mouse splenocytes assessed as inhibition of TNFalpha production at 10 uM after 72 hrs by E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2017
Entry Details Article
PubMed