BDBM50146610 CHEMBL368558::[(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-(4-methoxy-phenyl)-pyrrolidin-3-yl]-acetic acid

SMILES CCCCN(CCCC)C(=O)CN1C[C@@H]([C@@H](CC(O)=O)[C@@H]1c1ccc(OC)cc1)c1ccc2OCOc2c1

InChI Key InChIKey=BXLNWOMSBXJQRE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50146610   

TargetEndothelin receptor type B(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50146610([(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-dibutylcarba...)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibitory concentration against Endothelin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50146610([(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-dibutylcarba...)
Affinity DataIC50: 0.5nMAssay Description:Ability to displace [125I]ET1 from the rat endothelin A receptor expressed in rat aorta smooth muscle cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed