BDBM50146608 (Z)-2-Benzo[1,3]dioxol-5-yl-3-(3-methoxy-benzyl)-4-(4-methoxy-phenyl)-4-oxo-but-2-enoic acid::CHEMBL177221

SMILES COc1ccc(cc1)C(=O)C(\Cc1cccc(OC)c1)=C(/C(O)=O)c1ccc2OCOc2c1

InChI Key InChIKey=CCYNDHNVPJAGKJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50146608   

TargetEndothelin receptor type B(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50146608((Z)-2-Benzo[1,3]dioxol-5-yl-3-(3-methoxy-benzyl)-4...)
Affinity DataIC50: 260nMAssay Description:Inhibitory concentration against Endothelin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50146608((Z)-2-Benzo[1,3]dioxol-5-yl-3-(3-methoxy-benzyl)-4...)
Affinity DataIC50: 3nMAssay Description:Ability to displace [125I]ET1 from the rat endothelin A receptor expressed in rat aorta smooth muscle cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed