BDBM50146577 CHEMBL102311::spirobenzoxazines analogues

SMILES COc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1CCC2(CCCC=C2)Cc2ccccc12

InChI Key InChIKey=ANLNFRWXCULLSI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50146577   

TargetVasopressin V2 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50146577(spirobenzoxazines analogues | CHEMBL102311)
Affinity DataIC50: 0.200nMAssay Description:In vitro inhibitory concentration against [3H]AVP binding to cloned human vasopressin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50146577(spirobenzoxazines analogues | CHEMBL102311)
Affinity DataIC50: 30nMAssay Description:In vitro inhibitory concentration against [3H]AVP binding to cloned human vasopressin V1a receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed