BDBM50146552 2-[7-Ethyl-6-(4-sulfamoyl-benzylamino)-7H-purin-2-ylamino]-4-methyl-thiazole-5-carboxylic acid ethyl ester::CHEMBL100503::ethyl 2-(7-ethyl-6-(4-sulfamoylbenzylamino)-7H-purin-2-ylamino)-4-methylthiazole-5-carboxylate

SMILES CCOC(=O)c1sc(Nc2nc(NCc3ccc(cc3)S(N)(=O)=O)c3n(CC)cnc3n2)nc1C

InChI Key InChIKey=QNLOLWMFEMGKAI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50146552   

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50146552(2-[7-Ethyl-6-(4-sulfamoyl-benzylamino)-7H-purin-2-...)
Affinity DataIC50: 2.97E+3nMAssay Description:Inhibition of Phosphodiesterase 3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50146552(2-[7-Ethyl-6-(4-sulfamoyl-benzylamino)-7H-purin-2-...)
Affinity DataIC50: 950nMAssay Description:Inhibition of Phosphodiesterase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed