BDBM50146473 2,2-Dimethyl-propionic acid 4-{2-(formyl-hydroxy-amino)-3-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonyl]-propylidene}-piperidin-1-yl ester::CHEMBL95414

SMILES [#6]-c1cc(-[#6]-[#8]-c2ccc(cc2)S(=O)(=O)[#6]-[#6](\[#6]=[#6]-2\[#6]-[#6]-[#7](-[#6]-[#6]-2)-[#8]-[#6](=O)C([#6])([#6])[#6])-[#7](-[#8])-[#6]=O)c2ccccc2n1

InChI Key InChIKey=HZNCNAGYECABJB-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50146473   

TargetMatrix metalloproteinase-17(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146473(2,2-Dimethyl-propionic acid 4-{2-(formyl-hydroxy-a...)
Affinity DataIC50: 550nMAssay Description:Inhibition of matrix metalloprotease-17More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146473(2,2-Dimethyl-propionic acid 4-{2-(formyl-hydroxy-a...)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146473(2,2-Dimethyl-propionic acid 4-{2-(formyl-hydroxy-a...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146473(2,2-Dimethyl-propionic acid 4-{2-(formyl-hydroxy-a...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50146473(2,2-Dimethyl-propionic acid 4-{2-(formyl-hydroxy-a...)
Affinity DataIC50: 3nMAssay Description:Inhibition of Tumor necrosis factor alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146473(2,2-Dimethyl-propionic acid 4-{2-(formyl-hydroxy-a...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed