BDBM50146443 3-Methyl-8-(1-methyl-1H-[1,2,4]triazol-3-ylmethylsulfanyl)-5-thiazol-2-yl-3,4-dihydro-2H-naphthalen-1-one::CHEMBL318873

SMILES CC1CC(=O)c2c(SCc3ncn(C)n3)ccc(-c3nccs3)c2C1

InChI Key InChIKey=OXUTXRZFYPFZEZ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50146443   

LigandPNGBDBM50146443(3-Methyl-8-(1-methyl-1H-[1,2,4]triazol-3-ylmethyls...)
Affinity DataKi:  1nMAssay Description:Inhibition of [3H]-Ro- 15-1788 binding to human GABA-A receptor alpha-5-beta-3-gamma-2 subunitsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
LigandPNGBDBM50146443(3-Methyl-8-(1-methyl-1H-[1,2,4]triazol-3-ylmethyls...)
Affinity DataKi:  16nMAssay Description:Inhibition of [3H]-Ro- 15-1788 binding to recombinant human gamma-aminobutyric-acid A receptor alpha-3-beta-3-gamma-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
LigandPNGBDBM50146443(3-Methyl-8-(1-methyl-1H-[1,2,4]triazol-3-ylmethyls...)
Affinity DataKi:  20nMAssay Description:Inhibition of [3H]-Ro- 15-1788 binding to recombinant human gamma-aminobutyric-acid A receptor alpha-2-beta-3-gamma-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
LigandPNGBDBM50146443(3-Methyl-8-(1-methyl-1H-[1,2,4]triazol-3-ylmethyls...)
Affinity DataKi:  38nMAssay Description:Inhibition of [3H]-Ro- 15-1788 binding to recombinant human gamma-aminobutyric-acid A receptor alpha-1-beta-3-gamma-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed