BDBM50146442 3-Methyl-5-thiazol-2-yl-8-(3H-[1,2,3]triazol-4-ylmethylsulfanyl)-3,4-dihydro-2H-naphthalen-1-one::CHEMBL95760

SMILES CC1CC(=O)c2c(SCc3cnn[nH]3)ccc(-c3nccs3)c2C1

InChI Key InChIKey=SFQDQVWLPSONMD-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50146442   

LigandPNGBDBM50146442(3-Methyl-5-thiazol-2-yl-8-(3H-[1,2,3]triazol-4-ylm...)
Affinity DataKi:  2.60nMAssay Description:Inhibition of [3H]-Ro- 15-1788 binding to human GABA-A receptor alpha-5-beta-3-gamma-2 subunitsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
LigandPNGBDBM50146442(3-Methyl-5-thiazol-2-yl-8-(3H-[1,2,3]triazol-4-ylm...)
Affinity DataKi:  36nMAssay Description:Inhibition of [3H]-Ro- 15-1788 binding to recombinant human gamma-aminobutyric-acid A receptor alpha-3-beta-3-gamma-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
LigandPNGBDBM50146442(3-Methyl-5-thiazol-2-yl-8-(3H-[1,2,3]triazol-4-ylm...)
Affinity DataKi:  57nMAssay Description:Inhibition of [3H]-Ro- 15-1788 binding to recombinant human gamma-aminobutyric-acid A receptor alpha-2-beta-3-gamma-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
LigandPNGBDBM50146442(3-Methyl-5-thiazol-2-yl-8-(3H-[1,2,3]triazol-4-ylm...)
Affinity DataKi:  92nMAssay Description:Inhibition of [3H]-Ro- 15-1788 binding to recombinant human gamma-aminobutyric-acid A receptor alpha-1-beta-3-gamma-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed