BDBM50146347 CHEMBL327306::Dimethyl-[(3aR,12bS)-1-(2,3,3a,12b-tetrahydro-1-oxa-8-thia-dibenzo[e,h]azulen-2-yl)methyl]-amine

SMILES CN(C)CC1C[C@H]2[C@H](O1)c1ccccc1Sc1ccccc21

InChI Key InChIKey=KWUQZAPLAOREKL-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50146347   

TargetHistamine H1 receptor(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50146347(Dimethyl-[(3aR,12bS)-1-(2,3,3a,12b-tetrahydro-1-ox...)
Affinity DataKi:  4.30nMAssay Description:Ability to displace [3H]pyrilamine from human cloned histamine H1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50146347(Dimethyl-[(3aR,12bS)-1-(2,3,3a,12b-tetrahydro-1-ox...)
Affinity DataKi:  25nMAssay Description:Ability to displace [3H]- mesulergine from human cloned 5-hydroxytryptamine 2C receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50146347(Dimethyl-[(3aR,12bS)-1-(2,3,3a,12b-tetrahydro-1-ox...)
Affinity DataKi:  31nMAssay Description:Ability to displace [125I]R91150 from human cloned 5-hydroxytryptamine 2A receptor expressed in L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed