BDBM50146329 (E)-3-[3-(2-Ethoxy-3,5-diisopropyl-phenyl)-benzo[d]isoxazol-5-yl]-but-2-enoic acid::CHEMBL328507

SMILES CCOc1c(cc(cc1-c1noc2ccc(cc12)C(\C)=C\C(O)=O)C(C)C)C(C)C

InChI Key InChIKey=RKEPFESSUYKZDD-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50146329   

TargetRetinoic acid receptor RXR-alpha(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50146329((E)-3-[3-(2-Ethoxy-3,5-diisopropyl-phenyl)-benzo[d...)
Affinity DataEC50:  1.02E+3nMAssay Description:Effective concentration for antagonistic activity against RXR-alpha expressed in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50146329((E)-3-[3-(2-Ethoxy-3,5-diisopropyl-phenyl)-benzo[d...)
Affinity DataKi:  648nMAssay Description:Ability to displace [3H]9-cis-RA from Retinoid X receptor alpha in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50146329((E)-3-[3-(2-Ethoxy-3,5-diisopropyl-phenyl)-benzo[d...)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to displace [3H]ATRA from Retinoic acid receptor gamma in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed