BDBM50146272 (2S,3R)-3-(3-Hydroxy-phenyl)-2-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-2,3-dihydro-benzo[1,4]oxathiin-6-ol::CHEMBL327320

SMILES Oc1cccc(c1)[C@H]1Sc2cc(O)ccc2O[C@H]1c1ccc(OCCN2CCCC2)cc1

InChI Key InChIKey=CABPHYRAHPMSMC-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50146272   

TargetEstrogen receptor beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50146272((2S,3R)-3-(3-Hydroxy-phenyl)-2-[4-(2-pyrrolidin-1-...)
Affinity DataIC50: 37nMAssay Description:Displacement of [3H]17-beta-estradiol from full length human estrogen receptor betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50146272((2S,3R)-3-(3-Hydroxy-phenyl)-2-[4-(2-pyrrolidin-1-...)
Affinity DataIC50: 1.70nMAssay Description:Potency in cellular transactivation assay utilizing HEK293 cells stably co-transfected with human estrogen receptor alpha and the alkaline phosphatas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50146272((2S,3R)-3-(3-Hydroxy-phenyl)-2-[4-(2-pyrrolidin-1-...)
Affinity DataIC50: 38nMAssay Description:Binding affinity for human estrogen receptor betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50146272((2S,3R)-3-(3-Hydroxy-phenyl)-2-[4-(2-pyrrolidin-1-...)
Affinity DataIC50: 1nMAssay Description:Binding affinity for human estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50146272((2S,3R)-3-(3-Hydroxy-phenyl)-2-[4-(2-pyrrolidin-1-...)
Affinity DataIC50: 0.900nMAssay Description:Displacement of [3H]17-beta-estradiol from full length human estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50146272((2S,3R)-3-(3-Hydroxy-phenyl)-2-[4-(2-pyrrolidin-1-...)
Affinity DataIC50: 40nMAssay Description:Potency in cellular transactivation assay utilizing HEK293 cells stably co-transfected with human estrogen receptor beta and the alkaline phosphatase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed