BDBM50146224 1,2-Diphenyl-1,2,3,4-tetrahydro-isoquinolin-6-ol::CHEMBL91052

SMILES Oc1ccc2C(N(CCc2c1)c1ccccc1)c1ccccc1

InChI Key InChIKey=BCVXRPDYMYWNQG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50146224   

TargetEstrogen receptor beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50146224(1,2-Diphenyl-1,2,3,4-tetrahydro-isoquinolin-6-ol |...)
Affinity DataIC50: 49nMAssay Description:In vitro concentration required to inhibit [3H]estradiol binding to human estrogen receptor beta expressed in 293T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50146224(1,2-Diphenyl-1,2,3,4-tetrahydro-isoquinolin-6-ol |...)
Affinity DataIC50: 31nMAssay Description:In vitro concentration required to inhibit [3H]estradiol binding to human estrogen receptor alpha expressed in 293T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed