BDBM50146207 4-(4-Hydroxy-phenyl)-2-(naphthalene-1-sulfonyl)-1,2,3,4-tetrahydro-isoquinolin-7-ol::CHEMBL93792

SMILES Oc1ccc(cc1)C1CN(Cc2cc(O)ccc12)S(=O)(=O)c1cccc2ccccc12

InChI Key InChIKey=LXRCRKABAIYOCQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50146207   

TargetEstrogen receptor beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50146207(4-(4-Hydroxy-phenyl)-2-(naphthalene-1-sulfonyl)-1,...)
Affinity DataIC50: 11nMAssay Description:In vitro concentration required to inhibit [3H]estradiol binding to human estrogen receptor beta expressed in 293T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50146207(4-(4-Hydroxy-phenyl)-2-(naphthalene-1-sulfonyl)-1,...)
Affinity DataIC50: 28nMAssay Description:In vitro concentration required to inhibit [3H]estradiol binding to human estrogen receptor alpha expressed in 293T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed