BDBM50146164 CHEMBL2143592

SMILES c1cc(ccc1C2=CNC=C(C2=O)C(=O)Nc3ccc(c(c3)F)Oc4ccnc(c4Cl)N)F

InChI Key InChIKey=PDYXPCKITKHFOZ-UHFFFAOYSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50146164   

TargetHepatocyte growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50146164(CHEMBL2143592)
Affinity DataIC50: 1.70nMAssay Description:Competitive inhibition of c-Met (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2017
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50146164(CHEMBL2143592)
Affinity DataIC50: 15nMAssay Description:Competitive inhibition of VEGFR2 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2017
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50146164(CHEMBL2143592)
Affinity DataIC50: 3nMAssay Description:Inhibition of Axl (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2017
Entry Details Article
PubMed
TargetMacrophage-stimulating protein receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50146164(CHEMBL2143592)
Affinity DataIC50: 3nMAssay Description:Inhibition of Ron (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2017
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50146164(CHEMBL2143592)
Affinity DataIC50: 3nMAssay Description:Inhibition of Flt-3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2017
Entry Details Article
PubMed