BDBM50146117 4-{(E)-2-[({[2,4-Dichloro-3-(2-methyl-4-piperidin-1-yl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-pyridin-2-ylmethyl-benzamide; Trihydrochloride::CHEMBL553897

SMILES CN(C(=O)CNC(=O)\C=C\c1ccc(cc1)C(=O)NCc1ccccn1)c1ccc(Cl)c(COc2cccc3c(cc(C)nc23)N2CCCCC2)c1Cl

InChI Key InChIKey=AXRYWEAVAZCNIT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50146117   

TargetB2 bradykinin receptor(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146117(4-{(E)-2-[({[2,4-Dichloro-3-(2-methyl-4-piperidin-...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of specific binding of [3H]BK at 1 nM to human bradykinin receptor B2 expressed in CHO cells by 50%.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetB2 bradykinin receptor(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146117(4-{(E)-2-[({[2,4-Dichloro-3-(2-methyl-4-piperidin-...)
Affinity DataIC50: 40nMAssay Description:Inhibition of specific binding of [3H]BK at 0.06 nM to bradykinin receptor B2 in guinea pig ileum membrane preparations by 50%.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed