BDBM50146105 4-((E)-2-{[({2,4-Dichloro-3-[4-(2-methoxy-ethylamino)-2-methyl-quinolin-8-yloxymethyl]-phenyl}-methyl-carbamoyl)-methyl]-carbamoyl}-vinyl)-N-methyl-benzamide; Dihydrochloride::CHEMBL542905

SMILES CNC(=O)c1ccc(\C=C\C(=O)NCC(=O)N(C)c2ccc(Cl)c(COc3cccc4c(NCCOC)cc(C)nc34)c2Cl)cc1

InChI Key InChIKey=VWGZMXQWLZLMPT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50146105   

TargetB2 bradykinin receptor(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146105(4-((E)-2-{[({2,4-Dichloro-3-[4-(2-methoxy-ethylami...)
Affinity DataIC50: 41nMAssay Description:Inhibition of specific binding of [3H]BK at 1 nM to human bradykinin receptor B2 expressed in CHO cells by 50%.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetB2 bradykinin receptor(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146105(4-((E)-2-{[({2,4-Dichloro-3-[4-(2-methoxy-ethylami...)
Affinity DataIC50: 49nMAssay Description:Inhibition of specific binding of [3H]BK at 0.06 nM to bradykinin receptor B2 in guinea pig ileum membrane preparations by 50%.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed