BDBM50146087 1,3-Dimethyl-8-[4-(4-phenyl-piperazin-1-yl)-butyl]-5,6,7,8-tetrahydro-1H-1,3,4b,8,9-pentaaza-fluorene-2,4-dione::CHEMBL86719

SMILES Cn1c2nc3N(CCCCN4CCN(CC4)c4ccccc4)CCCn3c2c(=O)n(C)c1=O

InChI Key InChIKey=MHMIJKZAFZPTOO-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50146087   

Target5-hydroxytryptamine receptor 1A(Rat)
Collegium Medicum of The Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50146087(1,3-Dimethyl-8-[4-(4-phenyl-piperazin-1-yl)-butyl]...)
Affinity DataKi:  2.10nMAssay Description:Ability to bind to central serotonin 5-hydroxytryptamine 1A receptor in vitro in hippocampus of the rat brain using [3H]8-OH-DPAT radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50146087(1,3-Dimethyl-8-[4-(4-phenyl-piperazin-1-yl)-butyl]...)
Affinity DataKi:  2.10nMAssay Description:Binding affinity to 5-HT1A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

Target5-hydroxytryptamine receptor 2A(Rat)
Collegium Medicum of The Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50146087(1,3-Dimethyl-8-[4-(4-phenyl-piperazin-1-yl)-butyl]...)
Affinity DataKi:  243nMAssay Description:Ability to bind to central serotonin 5-hydroxytryptamine 2A receptor in vitro in cortex of the rat brain using [3H]ketanserin radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50146087(1,3-Dimethyl-8-[4-(4-phenyl-piperazin-1-yl)-butyl]...)
Affinity DataKi:  243nMAssay Description:Binding affinity to 5-HT2A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article