BDBM50145945 CHEMBL3764278

SMILES CN1CCCN(Cc2ccc(cc2)-c2ccc(CN3CCCN(C)CC3)c(F)c2F)CC1

InChI Key InChIKey=MRNZJSWWGMFFPS-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50145945   

TargetCholine kinase alpha(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145945(CHEMBL3764278)
Affinity DataIC50: 233nMAssay Description:Inhibition of human N-terminal truncated ChoKalpha1 (75 to 457 residues) using choline chloride as substrate measured over 10 to 30 mins by coupled A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2017
Entry Details Article
PubMed
TargetCholine kinase alpha(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145945(CHEMBL3764278)
Affinity DataKd:  21nMAssay Description:Binding affinity to human N-terminal truncated ChoKalpha1 (75 to 457 residues) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2017
Entry Details Article
PubMed