BDBM50145471 5-(4-(benzyloxy)benzyl)thiazolidine-2,4-dione::5-(4-Benzyloxy-benzyl)-thiazolidine-2,4-dione::CHEMBL316370::US8637558, 116::US8637558, 124

SMILES Oc1[nH]c(=O)sc1Cc1ccc(OCc2ccccc2)cc1

InChI Key InChIKey=FTZBHLNLLKSNNO-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50145471   

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Industry-Academic Cooperation Foundation, Chosun University

US Patent
LigandPNGBDBM50145471(US8637558, 116 | CHEMBL316370 | 5-(4-Benzyloxy-ben...)
Affinity DataIC50: 1.26E+3nMpH: 7.5Assay Description:Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2014
Entry Details
Go to US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Industry-Academic Cooperation Foundation, Chosun University

US Patent
LigandPNGBDBM50145471(US8637558, 116 | CHEMBL316370 | 5-(4-Benzyloxy-ben...)
Affinity DataIC50: 5.25E+3nMpH: 7.5Assay Description:Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2014
Entry Details
Go to US Patent

TargetFree fatty acid receptor 1(Human)
Suez Canal University

Curated by ChEMBL
LigandPNGBDBM50145471(US8637558, 116 | CHEMBL316370 | 5-(4-Benzyloxy-ben...)
Affinity DataEC50:  6.56E+3nMAssay Description:Agonist activity at human FFAR1 expressed in CHO-K1 cells assessed as calcium flux measured for 100 secs by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2017
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Suez Canal University

Curated by ChEMBL
LigandPNGBDBM50145471(US8637558, 116 | CHEMBL316370 | 5-(4-Benzyloxy-ben...)
Affinity DataEC50:  6.18E+3nMAssay Description:Agonist activity at human GPR40 by FLIPR assay in presence of 1% BSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed