BDBM50145415 1-(2-chloro-2-phenylethyl)-N,N-diethyl-6-(methylthio)-1H-pyrazolo[3,4-d]pyrimidin-4-amine::CHEMBL83847::[1-(2-Chloro-2-phenyl-ethyl)-6-methylsulfanyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl]-diethyl-amine

SMILES CCN(CC)c1nc(SC)nc2n(CC(Cl)c3ccccc3)ncc12

InChI Key InChIKey=IROGZYPJAAVIAT-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50145415   

TargetTyrosine-protein kinase ABL1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50145415([1-(2-Chloro-2-phenyl-ethyl)-6-methylsulfanyl-1H-p...)
Affinity DataKi:  400nMAssay Description:Inhibition of human recombinant Abl by filter-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50145415([1-(2-Chloro-2-phenyl-ethyl)-6-methylsulfanyl-1H-p...)
Affinity DataKi:  500nMAssay Description:Inhibitory activity against Src in cell free assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50145415([1-(2-Chloro-2-phenyl-ethyl)-6-methylsulfanyl-1H-p...)
Affinity DataKi:  500nMAssay Description:Inhibition of human recombinant c-Src by filter-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50145415([1-(2-Chloro-2-phenyl-ethyl)-6-methylsulfanyl-1H-p...)
Affinity DataKi:  501nMAssay Description:Inhibition of c-SrcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed