BDBM50145232 CHEMBL311229::{4-[(9-Methyl-4,5-dihydro-6-oxa-3-thia-1-aza-benzo[e]azulen-2-ylamino)-methyl]-piperidin-1-yl}-(R)-tetrahydro-furan-2-yl-methanone

SMILES Cc1ccc2OCCc3sc(NCC4CCN(CC4)C(=O)[C@H]4CCCO4)nc3-c2c1

InChI Key InChIKey=PQAHPKKBCMEGKW-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50145232   

TargetNeuropeptide Y receptor type 5(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50145232({4-[(9-Methyl-4,5-dihydro-6-oxa-3-thia-1-aza-benzo...)
Affinity DataIC50: 5nMAssay Description:In vitro binding affinity against human neuropeptide Y5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50145232({4-[(9-Methyl-4,5-dihydro-6-oxa-3-thia-1-aza-benzo...)
Affinity DataIC50: 3.00E+4nMAssay Description:In vitro binding affinity against rat neuropeptide Y2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 4(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50145232({4-[(9-Methyl-4,5-dihydro-6-oxa-3-thia-1-aza-benzo...)
Affinity DataIC50: 3.00E+4nMAssay Description:In vitro binding affinity against rat neuropeptide Y4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Rat)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50145232({4-[(9-Methyl-4,5-dihydro-6-oxa-3-thia-1-aza-benzo...)
Affinity DataIC50: 2.90nMAssay Description:In vitro binding affinity against rat neuropeptide Y5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50145232({4-[(9-Methyl-4,5-dihydro-6-oxa-3-thia-1-aza-benzo...)
Affinity DataIC50: 3.00E+4nMAssay Description:In vitro binding affinity against rat neuropeptide Y1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50145232({4-[(9-Methyl-4,5-dihydro-6-oxa-3-thia-1-aza-benzo...)
Affinity DataIC50: 40nMAssay Description:In vitro binding affinity against human neuropeptide Y5 receptor measured as Ca+ responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed