BDBM50144963 CHEMBL3763358

SMILES COCCOc1cc2c(ncnc2cc1OC)-n1nc(nc1N)-c1ccccn1

InChI Key InChIKey=ZXNSGRMQSJUSGX-UHFFFAOYSA-N

Data  1 IC50  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50144963   

TargetSerine-protein kinase ATM(Human)
Duke University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50144963(CHEMBL3763358)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of ATM kinase in human MCF7 cells after 1 hr by immunofluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Nek6(Human)
Duke University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50144963(CHEMBL3763358)
Affinity DataKd:  130nMAssay Description:Binding affinity to human NEK6More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Duke University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50144963(CHEMBL3763358)
Affinity DataKd:  41nMAssay Description:Binding affinity to human TYK2 JH2 domain pseudokinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Nek9(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50144963(CHEMBL3763358)
Affinity DataKd:  380nMAssay Description:Inhibition of NEK9 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed