BDBM50144787 (S)-2-(2,6-Dichloro-benzoylamino)-3-[2-(2,6-dichloro-phenyl)-benzooxazol-5-yl]-propionic acid::CHEMBL308346

SMILES OC(=O)[C@H](Cc1ccc2oc(nc2c1)-c1c(Cl)cccc1Cl)NC(=O)c1c(Cl)cccc1Cl

InChI Key InChIKey=XYRKHQUYEVMHKJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50144787   

TargetIntegrin alpha-4/beta-7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144787((S)-2-(2,6-Dichloro-benzoylamino)-3-[2-(2,6-dichlo...)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of Mn2+ activated state of alpha4-beta7 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144787((S)-2-(2,6-Dichloro-benzoylamino)-3-[2-(2,6-dichlo...)
Affinity DataIC50: 0.790nMAssay Description:Inhibition of Mn2+ activated state of very late antigen 4 (VLA-4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144787((S)-2-(2,6-Dichloro-benzoylamino)-3-[2-(2,6-dichlo...)
Affinity DataIC50: 52nMAssay Description:Inhibition of [Ca2+]/Mg2+ unactivated state of very late antigen 4 (VLA-4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed