BDBM50144781 6,6a-Dihydro-5H-benzo[a]phenoxazine-3,9-diol::CHEMBL77851

SMILES Oc1ccc2C3=Nc4ccc(O)cc4OC3CCc2c1

InChI Key InChIKey=YVCCFKDKQAZFTM-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50144781   

TargetEstrogen receptor beta(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144781(6,6a-Dihydro-5H-benzo[a]phenoxazine-3,9-diol | CHE...)
Affinity DataEC50:  240nMAssay Description:Ability to activate estrogen receptor 2-mediated transcription.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144781(6,6a-Dihydro-5H-benzo[a]phenoxazine-3,9-diol | CHE...)
Affinity DataIC50: 2.60E+3nMAssay Description:Binding affinity towards estrogen receptor beta by [3H]17-beta-estradiol displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144781(6,6a-Dihydro-5H-benzo[a]phenoxazine-3,9-diol | CHE...)
Affinity DataEC50:  1.20E+4nMAssay Description:Ability to activate estrogen receptor 1-mediated transcription.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144781(6,6a-Dihydro-5H-benzo[a]phenoxazine-3,9-diol | CHE...)
Affinity DataIC50: 6.00E+3nMAssay Description:Ability to activate estrogen receptor 1-mediated transcription.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed