BDBM50144772 3-(4-Hydroxy-phenyl)-2H-benzo[1,4]oxazin-7-ol::CHEMBL77794

SMILES Oc1ccc(cc1)C1=Nc2ccc(O)cc2OC1

InChI Key InChIKey=OZTZEJHIEFWILS-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50144772   

TargetEstrogen receptor beta(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144772(3-(4-Hydroxy-phenyl)-2H-benzo[1,4]oxazin-7-ol | CH...)
Affinity DataEC50:  160nMAssay Description:Ability to activate estrogen receptor 2-mediated transcription.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144772(3-(4-Hydroxy-phenyl)-2H-benzo[1,4]oxazin-7-ol | CH...)
Affinity DataEC50:  6.90E+3nMAssay Description:Ability to activate estrogen receptor 1-mediated transcription.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144772(3-(4-Hydroxy-phenyl)-2H-benzo[1,4]oxazin-7-ol | CH...)
Affinity DataIC50: 2.90E+3nMAssay Description:Binding affinity towards estrogen receptor beta by [3H]17-beta-estradiol displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144772(3-(4-Hydroxy-phenyl)-2H-benzo[1,4]oxazin-7-ol | CH...)
Affinity DataIC50: 1.60E+4nMAssay Description:Binding affinity towards estrogen receptor alpha by [3H]17-beta-estradiol displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed