BDBM50144481 CHEMBL304102::N-(3-Dibenzylamino-2-ethyl-phenyl)-methanesulfonamide

SMILES CCc1c(NS(C)(=O)=O)cccc1N(Cc1ccccc1)Cc1ccccc1

InChI Key InChIKey=VHQBARXHNQJQJO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50144481   

TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144481(N-(3-Dibenzylamino-2-ethyl-phenyl)-methanesulfonam...)
Affinity DataIC50: 270nMAssay Description:Functional activity towards human Glucocorticoid receptor in genetically engineered cell line containing glucocorticoid response element and reporter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144481(N-(3-Dibenzylamino-2-ethyl-phenyl)-methanesulfonam...)
Affinity DataIC50: 12nMAssay Description:Binding affinity against human Glucocorticoid receptor (GR) using [3H]dexamethasone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144481(N-(3-Dibenzylamino-2-ethyl-phenyl)-methanesulfonam...)
Affinity DataIC50: 12nMAssay Description:Inhibition of [3H]dexamethasone binding to glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144481(N-(3-Dibenzylamino-2-ethyl-phenyl)-methanesulfonam...)
Affinity DataIC50: 270nMAssay Description:Inhibition of glucocorticoid receptor Dexamethasone responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed