BDBM50144467 CHEMBL70381::N-{3-[Benzyl-(4-chloro-2-fluoro-benzyl)-amino]-2-methyl-phenyl}-methanesulfonamide

SMILES Cc1c(NS(C)(=O)=O)cccc1N(Cc1ccccc1)Cc1ccc(Cl)cc1F

InChI Key InChIKey=WWKUDAJCCSNRRV-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50144467   

TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144467(N-{3-[Benzyl-(4-chloro-2-fluoro-benzyl)-amino]-2-m...)
Affinity DataIC50: 210nMAssay Description:Functional activity towards human Glucocorticoid receptor in genetically engineered cell line containing glucocorticoid response element and reporter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144467(N-{3-[Benzyl-(4-chloro-2-fluoro-benzyl)-amino]-2-m...)
Affinity DataIC50: 4.00E+3nMAssay Description:Displacement of [3H]dexamethasone from human mineralocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144467(N-{3-[Benzyl-(4-chloro-2-fluoro-benzyl)-amino]-2-m...)
Affinity DataIC50: 300nMAssay Description:Displacement of [3H]dexamethasone from human androgen receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144467(N-{3-[Benzyl-(4-chloro-2-fluoro-benzyl)-amino]-2-m...)
Affinity DataIC50: 790nMAssay Description:Displacement of [3H]dexamethasone from human progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144467(N-{3-[Benzyl-(4-chloro-2-fluoro-benzyl)-amino]-2-m...)
Affinity DataIC50: 5.70nMAssay Description:Binding affinity against human Glucocorticoid receptor (GR) using [3H]dexamethasone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144467(N-{3-[Benzyl-(4-chloro-2-fluoro-benzyl)-amino]-2-m...)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of [3H]dexamethasone binding to glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144467(N-{3-[Benzyl-(4-chloro-2-fluoro-benzyl)-amino]-2-m...)
Affinity DataIC50: 210nMAssay Description:Inhibition of glucocorticoid receptor Dexamethasone responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed