BDBM50144457 CHEMBL419633::N-(3-Dibenzylamino-2-methyl-phenyl)-methanesulfonamide

SMILES Cc1c(NS(C)(=O)=O)cccc1N(Cc1ccccc1)Cc1ccccc1

InChI Key InChIKey=WGGMBWMYJSVPSG-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50144457   

TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144457(N-(3-Dibenzylamino-2-methyl-phenyl)-methanesulfona...)
Affinity DataIC50: 250nMAssay Description:Functional activity towards human Glucocorticoid receptor in genetically engineered cell line containing glucocorticoid response element and reporter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144457(N-(3-Dibenzylamino-2-methyl-phenyl)-methanesulfona...)
Affinity DataIC50: 28nMAssay Description:Binding affinity against human Glucocorticoid receptor (GR) using [3H]dexamethasone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144457(N-(3-Dibenzylamino-2-methyl-phenyl)-methanesulfona...)
Affinity DataIC50: 7.60E+3nMAssay Description:Displacement of [3H]dexamethasone from human progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144457(N-(3-Dibenzylamino-2-methyl-phenyl)-methanesulfona...)
Affinity DataIC50: 170nMAssay Description:Displacement of [3H]dexamethasone from human androgen receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144457(N-(3-Dibenzylamino-2-methyl-phenyl)-methanesulfona...)
Affinity DataIC50: 310nMAssay Description:Displacement of [3H]dexamethasone from human mineralocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144457(N-(3-Dibenzylamino-2-methyl-phenyl)-methanesulfona...)
Affinity DataIC50: 28nMAssay Description:Inhibition of [3H]dexamethasone binding to glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144457(N-(3-Dibenzylamino-2-methyl-phenyl)-methanesulfona...)
Affinity DataIC50: 250nMAssay Description:Inhibition of glucocorticoid receptor Dexamethasone responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144457(N-(3-Dibenzylamino-2-methyl-phenyl)-methanesulfona...)
Affinity DataIC50: 250nMAssay Description:Inhibition of glucocorticoid receptor Dexamethasone response in reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144457(N-(3-Dibenzylamino-2-methyl-phenyl)-methanesulfona...)
Affinity DataIC50: 28nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed