BDBM50144308 8-Methyl-3-(3-thiophen-3-yl-phenyl)-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester::CHEMBL303232

SMILES COC(=O)C1C2CCC(CC1c1cccc(c1)-c1ccsc1)N2C

InChI Key

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50144308   

TargetSodium-dependent dopamine transporter(Rat)
Yale School of Medicine

Curated by ChEMBL
LigandPNGBDBM50144308(8-Methyl-3-(3-thiophen-3-yl-phenyl)-8-aza-bicyclo[...)
Affinity DataKi:  24nMAssay Description:Binding affinity to dopamine transporter (DAT) in rat forebrain tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Yale School of Medicine

Curated by ChEMBL
LigandPNGBDBM50144308(8-Methyl-3-(3-thiophen-3-yl-phenyl)-8-aza-bicyclo[...)
Affinity DataKi:  30nMAssay Description:Binding affinity to dopamine transporter in membranes of cells selectively expressing the human genes for DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Yale School of Medicine

Curated by ChEMBL
LigandPNGBDBM50144308(8-Methyl-3-(3-thiophen-3-yl-phenyl)-8-aza-bicyclo[...)
Affinity DataKi:  74nMAssay Description:Binding affinity to serotonin transporter (SERT) in membranes of cells selectively expressing the human genes for SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Yale School of Medicine

Curated by ChEMBL
LigandPNGBDBM50144308(8-Methyl-3-(3-thiophen-3-yl-phenyl)-8-aza-bicyclo[...)
Affinity DataKi:  83nMAssay Description:Binding affinity to serotonin transporter (SERT) in rat forebrain tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransporter(Rat)
Yale School of Medicine

Curated by ChEMBL
LigandPNGBDBM50144308(8-Methyl-3-(3-thiophen-3-yl-phenyl)-8-aza-bicyclo[...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to norepinephrine (NE) transporter in rat forebrain tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Yale School of Medicine

Curated by ChEMBL
LigandPNGBDBM50144308(8-Methyl-3-(3-thiophen-3-yl-phenyl)-8-aza-bicyclo[...)
Affinity DataKi: >2.00E+4nMAssay Description:Binding affinity to norepinephrine (NE) transporter in membranes of cells selectively expressing the human genes for NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed