BDBM50144252 CHEMBL68113::N,N-Diethyl-4-{[(1R,5S)-8-phenethyl-8-aza-bicyclo[3.2.1]oct-(3E)-ylidene]-phenyl-methyl}-benzamide

SMILES CCN(CC)C(=O)c1ccc(cc1)C(=C1/C[C@@H]2CC[C@H](C1)N2CCc1ccccc1)\c1ccccc1

InChI Key

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50144252   

TargetDelta-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50144252(N,N-Diethyl-4-{[(1R,5S)-8-phenethyl-8-aza-bicyclo[...)
Affinity DataEC50:  1.39E+3nMAssay Description:Effective concentration against stimulation of [35S]GTP-gamma-S, binding in CHO cells transfected with the human opioid receptor delta 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50144252(N,N-Diethyl-4-{[(1R,5S)-8-phenethyl-8-aza-bicyclo[...)
Affinity DataKi:  42nMAssay Description:Binding affinity for delta opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50144252(N,N-Diethyl-4-{[(1R,5S)-8-phenethyl-8-aza-bicyclo[...)
Affinity DataKi:  42nMAssay Description:In vitro binding affinity towards opioid receptor delta 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50144252(N,N-Diethyl-4-{[(1R,5S)-8-phenethyl-8-aza-bicyclo[...)
Affinity DataKi:  317nMAssay Description:Binding affinity for mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50144252(N,N-Diethyl-4-{[(1R,5S)-8-phenethyl-8-aza-bicyclo[...)
Affinity DataKi:  317nMAssay Description:Binding affinity towards opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed