BDBM50144231 CHEMBL66668::N,N-Diethyl-4-{phenyl-[8-(2-thiophen-2-yl-ethyl)-8-aza-bicyclo[3.2.1]oct-3-ylidene]-methyl}-benzamide

SMILES [#6]-[#6]-[#7](-[#6]-[#6])-[#6](=O)-c1ccc(cc1)-[#6](=[#6]-1\[#6]-[#6]-2-[#6]-[#6]-[#6](-[#6]-1)-[#7]-2-[#6]-[#6]-c1cccs1)\c1ccccc1

InChI Key InChIKey=FARUNQLOGMDFBC-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50144231   

TargetDelta-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50144231(N,N-Diethyl-4-{phenyl-[8-(2-thiophen-2-yl-ethyl)-8...)
Affinity DataEC50:  1.35E+3nMAssay Description:Effective concentration against stimulation of [35S]GTP-gamma-S, binding in CHO cells transfected with the human opioid receptor delta 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50144231(N,N-Diethyl-4-{phenyl-[8-(2-thiophen-2-yl-ethyl)-8...)
Affinity DataKi:  13nMAssay Description:Binding affinity for delta opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50144231(N,N-Diethyl-4-{phenyl-[8-(2-thiophen-2-yl-ethyl)-8...)
Affinity DataKi:  1.28E+3nMAssay Description:Binding affinity for mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed