BDBM50144188 CHEMBL417202::N-[1-Methoxy-6-(3-methylamino-phenyl)-6H-benzo[c]chromen-8-yl]-methanesulfonamide

SMILES CNc1cccc(c1)C1Oc2cccc(OC)c2-c2ccc(NS(C)(=O)=O)cc12

InChI Key InChIKey=JZDXQXQFWMXKGG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50144188   

TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144188(N-[1-Methoxy-6-(3-methylamino-phenyl)-6H-benzo[c]c...)
Affinity DataIC50: 23nMAssay Description:Displacement of [3H]dexamethasone from human Glucocorticoid receptor (GR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144188(N-[1-Methoxy-6-(3-methylamino-phenyl)-6H-benzo[c]c...)
Affinity DataIC50: 180nMAssay Description:Effect on human Glucocorticoid receptor (GR) in a whole cell assay to measure functional cellular GR-antagonism (GRAF)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed