BDBM50144178 CHEMBL303071::N-(6-Cyclohexyl-1-methoxy-6H-benzo[c]chromen-8-yl)-methanesulfonamide

SMILES COc1cccc2OC(C3CCCCC3)c3cc(NS(C)(=O)=O)ccc3-c12

InChI Key InChIKey=UYCHJDRKQKLTMT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50144178   

TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144178(N-(6-Cyclohexyl-1-methoxy-6H-benzo[c]chromen-8-yl)...)
Affinity DataIC50: 47nMAssay Description:Displacement of [3H]dexamethasone from human Glucocorticoid receptor (GR); Value ranges from 43-50 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144178(N-(6-Cyclohexyl-1-methoxy-6H-benzo[c]chromen-8-yl)...)
Affinity DataIC50: 630nMAssay Description:Effect on human Glucocorticoid receptor (GR) in a whole cell assay to measure functional cellular GR-antagonism (GRAF)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed