BDBM50144173 CHEMBL65221::N-(1-Difluoromethoxy-6-phenyl-6H-benzo[c]chromen-8-yl)-methanesulfonamide

SMILES CS(=O)(=O)Nc1ccc-2c(c1)C(Oc1cccc(OC(F)F)c-21)c1ccccc1

InChI Key InChIKey=WFSBONJXUAXVJH-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50144173   

TargetEstrogen receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144173(N-(1-Difluoromethoxy-6-phenyl-6H-benzo[c]chromen-8...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]estradiol from human estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144173(N-(1-Difluoromethoxy-6-phenyl-6H-benzo[c]chromen-8...)
Affinity DataIC50: 8.73E+3nMAssay Description:Displacement of [3H]mibolerone from human Androgen receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144173(N-(1-Difluoromethoxy-6-phenyl-6H-benzo[c]chromen-8...)
Affinity DataIC50: 162nMAssay Description:Displacement of [3H]aldosterone from human Mineralocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144173(N-(1-Difluoromethoxy-6-phenyl-6H-benzo[c]chromen-8...)
Affinity DataIC50: 367nMAssay Description:Displacement of [3H]progesterone from human Progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144173(N-(1-Difluoromethoxy-6-phenyl-6H-benzo[c]chromen-8...)
Affinity DataIC50: 57nMAssay Description:Displacement of [3H]dexamethasone from human Glucocorticoid receptor (GR); Value ranges from 150-220 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144173(N-(1-Difluoromethoxy-6-phenyl-6H-benzo[c]chromen-8...)
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]dexamethasone from human Glucocorticoid receptor (GR); Value ranges from 2-2 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed