BDBM50144169 CHEMBL65657::N-[6-(4-Fluoro-phenyl)-1-methoxy-6H-benzo[c]chromen-8-yl]-methanesulfonamide

SMILES COc1cccc2OC(c3ccc(F)cc3)c3cc(NS(C)(=O)=O)ccc3-c12

InChI Key InChIKey=JFBQVFCNTWRGTG-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50144169   

TargetAndrogen receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144169(N-[6-(4-Fluoro-phenyl)-1-methoxy-6H-benzo[c]chrome...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]mibolerone from human Androgen receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144169(N-[6-(4-Fluoro-phenyl)-1-methoxy-6H-benzo[c]chrome...)
Affinity DataIC50: 29nMAssay Description:Displacement of [3H]dexamethasone from human Glucocorticoid receptor (GR); Value ranges from 23-33 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144169(N-[6-(4-Fluoro-phenyl)-1-methoxy-6H-benzo[c]chrome...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]estradiol from human estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144169(N-[6-(4-Fluoro-phenyl)-1-methoxy-6H-benzo[c]chrome...)
Affinity DataIC50: 2.48E+3nMAssay Description:Displacement of [3H]aldosterone from human Mineralocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144169(N-[6-(4-Fluoro-phenyl)-1-methoxy-6H-benzo[c]chrome...)
Affinity DataIC50: 1.16E+3nMAssay Description:Displacement of [3H]progesterone from human Progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed