BDBM50144151 3-(8-Methanesulfonylamino-1-methoxy-6H-benzo[c]chromen-6-yl)-benzoic acid ethyl ester::CHEMBL302442

SMILES CCOC(=O)c1cccc(c1)C1Oc2cccc(OC)c2-c2ccc(NS(C)(=O)=O)cc12

InChI Key InChIKey=FSSLOFIETJPRRA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50144151   

TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144151(3-(8-Methanesulfonylamino-1-methoxy-6H-benzo[c]chr...)
Affinity DataIC50: 31nMAssay Description:Displacement of [3H]dexamethasone from human Glucocorticoid receptor (GR); Value ranges from 28-34 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144151(3-(8-Methanesulfonylamino-1-methoxy-6H-benzo[c]chr...)
Affinity DataIC50: 296nMAssay Description:Effect on human Glucocorticoid receptor (GR) in a whole cell assay to measure functional cellular GR-antagonism (GRAF)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed