BDBM50144150 CHEMBL293388::N-(1-Methoxy-6-thiophen-2-yl-6H-benzo[c]chromen-8-yl)-methanesulfonamide

SMILES COc1cccc2OC(c3cccs3)c3cc(NS(C)(=O)=O)ccc3-c12

InChI Key InChIKey=YWPNXVQAAHGWCZ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50144150   

TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144150(N-(1-Methoxy-6-thiophen-2-yl-6H-benzo[c]chromen-8-...)
Affinity DataIC50: 66nMAssay Description:Displacement of [3H]dexamethasone from human Glucocorticoid receptor (GR); Value ranges from 150-220 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144150(N-(1-Methoxy-6-thiophen-2-yl-6H-benzo[c]chromen-8-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]mibolerone from human Androgen receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144150(N-(1-Methoxy-6-thiophen-2-yl-6H-benzo[c]chromen-8-...)
Affinity DataIC50: 2.25E+3nMAssay Description:Displacement of [3H]aldosterone from human Mineralocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144150(N-(1-Methoxy-6-thiophen-2-yl-6H-benzo[c]chromen-8-...)
Affinity DataIC50: 450nMAssay Description:Displacement of [3H]progesterone from human Progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144150(N-(1-Methoxy-6-thiophen-2-yl-6H-benzo[c]chromen-8-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]estradiol from human estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144150(N-(1-Methoxy-6-thiophen-2-yl-6H-benzo[c]chromen-8-...)
Affinity DataIC50: 7nMAssay Description:Displacement of [3H]dexamethasone from human Glucocorticoid receptor (GR); Value ranges from 6-8 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed