BDBM50144149 CHEMBL65354::N-[6-(3-Fluoro-phenyl)-1-methoxy-6H-benzo[c]chromen-8-yl]-methanesulfonamide

SMILES COc1cccc2OC(c3cccc(F)c3)c3cc(NS(C)(=O)=O)ccc3-c12

InChI Key InChIKey=VYJSUSIGTRGXQC-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50144149   

TargetEstrogen receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144149(N-[6-(3-Fluoro-phenyl)-1-methoxy-6H-benzo[c]chrome...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]estradiol from human estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144149(N-[6-(3-Fluoro-phenyl)-1-methoxy-6H-benzo[c]chrome...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]mibolerone from human Androgen receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144149(N-[6-(3-Fluoro-phenyl)-1-methoxy-6H-benzo[c]chrome...)
Affinity DataIC50: 3nMAssay Description:Displacement of [3H]dexamethasone from human Glucocorticoid receptor (GR); Value ranges from 3-4 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144149(N-[6-(3-Fluoro-phenyl)-1-methoxy-6H-benzo[c]chrome...)
Affinity DataIC50: 683nMAssay Description:Displacement of [3H]aldosterone from human Mineralocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144149(N-[6-(3-Fluoro-phenyl)-1-methoxy-6H-benzo[c]chrome...)
Affinity DataIC50: 476nMAssay Description:Displacement of [3H]progesterone from human Progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144149(N-[6-(3-Fluoro-phenyl)-1-methoxy-6H-benzo[c]chrome...)
Affinity DataIC50: 3nMAssay Description:Displacement of [3H]dexamethasone from human Glucocorticoid receptor (GR); Value ranges from 3-4 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed