BDBM50143997 CHEMBL3759562

SMILES SCCCCCCNC(=O)c1cc(n[nH]1)-c1ccncc1

InChI Key InChIKey=KYZMEJZVXICXQX-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50143997   

TargetHistone deacetylase(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50143997(CHEMBL3759562)
Affinity DataIC50: 8nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using Boc-Lys(Ac)-AMC as substrate preincubated for 15 mins followed by substrate addition meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50143997(CHEMBL3759562)
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human HDAC3 using Boc-Lys(Ac)-AMC as substrate preincubated for 15 mins followed by substrate addition measured after 60 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50143997(CHEMBL3759562)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human HDAC1 using Boc-Lys(Ac)-AMC as substrate preincubated for 15 mins followed by substrate addition measured after 60 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50143997(CHEMBL3759562)
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant human HDAC6 using Boc-Lys(Ac)-AMC as substrate preincubated for 15 mins followed by substrate addition measured after 60 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50143997(CHEMBL3759562)
Affinity DataIC50: 72nMAssay Description:Inhibition of recombinant human HDAC2 using Boc-Lys(Ac)-AMC as substrate preincubated for 15 mins followed by substrate addition measured after 60 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50143997(CHEMBL3759562)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human HDAC11 using Boc-Lys(TFA)-AMC as substrate preincubated for 15 mins followed by substrate addition measured after 60 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50143997(CHEMBL3759562)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human HDAC8 using Boc-Lys(TFA)-AMC as substrate preincubated for 15 mins followed by substrate addition measured after 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50143997(CHEMBL3759562)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human HDAC4 using Boc-Lys(TFA)-AMC as substrate preincubated for 15 mins followed by substrate addition measured after 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed