BDBM50143835 (E)-3-[4-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-ylmethyl)-furan-2-yl]-acrylic acid::CHEMBL63048

SMILES CC1(C)CCC(C)(C)c2cc(Cc3coc(\C=C\C(O)=O)c3)ccc12

InChI Key InChIKey=GPLSMLHEZAREAH-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50143835   

TargetRetinoic acid receptor alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50143835((E)-3-[4-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-n...)
Affinity DataEC50:  57nMAssay Description:Effective concentration for retinoic acid receptor alpha induced lipogenesis in C3H10T1/2 clone 8 fibroblast cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50143835((E)-3-[4-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-n...)
Affinity DataKi:  138nMAssay Description:Binding affinity for retinoid X receptor alpha (RXRalpha), using 9-cis-[3H]-retinoic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50143835((E)-3-[4-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-n...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity for retinoic acid receptor alpha (RARalpha), using 9-cis-[3H]-retinoic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed